Antiaging compounds: (-)deprenyl (selegeline) and (-)1-(benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective highly potent enhancer of the impulse propagation mediated release of catecholamine and serotonin in the brain.
CNS Drug Rev
; 7(3): 317-45, 2001.
Article
em En
| MEDLINE
| ID: mdl-11607046
ABSTRACT
Hundreds of millions of people now die over the age of 80 years primarily due to twentieth century progress in hygiene, chemotherapy, and immunology. With a longer average lifespan, the need to improve quality of life during the latter decades is more compelling. "Aging--The Epidemic of the New Millenium," a recent international conference (Monte Carlo, June 17-18, 2000), showed with peculiar clarity that a safe and efficient drug strategy to slow the age-related decay of brain performance is still missing. This review summarizes the physiologic and pharmacologic arguments in favor of a peculiar lifelong prophylactic medication with reasonable chances to keep in check brain aging and decrease the precipitation of age-related neurological diseases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzofuranos
/
Encéfalo
/
Envelhecimento
/
Selegilina
/
Catecolaminas
/
Serotonina
/
Fármacos Neuroprotetores
Aspecto:
Patient_preference
Limite:
Animals
/
Humans
Idioma:
En
Revista:
CNS Drug Rev
Assunto da revista:
FARMACOLOGIA
/
NEUROLOGIA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Hungria