[Erythropoiesis disorders and other central autoimmune anemias]. / Erythroblastopénie et autres anémies centrales auto-immunes.
Rev Prat
; 51(14): 1547-51, 2001 Sep 15.
Article
em Fr
| MEDLINE
| ID: mdl-11757270
ABSTRACT
Immune-mediated acquired disorders of erythropoiesis can result in pure red cell aplasia or ineffective erythropoiesis. Erythropoiesis can be suppressed or impaired by humoral or cellular mechanisms. In vitro inhibition of erythroid colony growth by humoral factors or lymphocytes is a strong argument for the immune origin of the disease. Classical aetiologies are thymoma and hematological malignancies such as chronic lymphocytic leukaemia. Clonal proliferation of T cells has also been incriminated. Recently, acquired circulating autoantibodies directed against erythropoietin have been detected in a case of pure red cell aplasia. Autoimmune mechanisms have also been suggested in two dyserythropoietic syndromes recently described.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Aplasia Pura de Série Vermelha
/
Eritropoese
/
Anemia
Limite:
Humans
Idioma:
Fr
Revista:
Rev Prat
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA