The influence of cisplatinum and goserelinum on the magnesium and calcium level in rat serum.

Klukowska, L; Nadulska, A; Dyba, S

Klukowska, L; Nadulska, A; Dyba, S.

Afiliação

Klukowska L; Department of Human Physiology, Medical University of Lublin.

Ann Univ Mariae Curie Sklodowska Med ; 56: 483-6, 2001.

Article em En | MEDLINE | ID: mdl-11977363

ABSTRACT

ABSTRACT

The influence of cisplatinum and goserelinum on the magnesium and calcium concentration in rat serum has been studied. The cisplatinum induces decrease in serum magnesium concentration (to 70%), and calcium concentration (to 63%). Goserelinum activity was similar to cisplatinum activity. The magnesium concentration decreased to 60%, and calcium to 44%. In condition of cisplatinum and goserelinum activity the hypomagnesemia and hypocalcemia were noted.

Assuntos

Cálcio/sangue; Cisplatino/farmacologia; Gosserrelina/farmacologia; Magnésio/sangue; Animais; Antineoplásicos/farmacologia; Hipocalcemia/induzido quimicamente; Ratos; Ratos Wistar

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Cisplatino / Gosserrelina / Magnésio Limite: Animals Idioma: En Revista: Ann Univ Mariae Curie Sklodowska Med Ano de publicação: 2001 Tipo de documento: Article

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