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[Controlled liberation of active principles by means of new galenic formulations]. / Liberación controlada de principios activos mediante el empleo de formulaciones galénicas.
Murillo, M; Espuelas, S; Prior, S; Vitas, A I; Renedo, M J; Goñi, M M; Irache, J M; Gamazo, C.
Afiliação
  • Murillo M; Departamento de Farmacia y Tecnología Farmacéutica, Universidad de Navarra.
Rev Med Univ Navarra ; 45(4): 19-34, 2001.
Article em Es | MEDLINE | ID: mdl-11985214
Drugs inside a conventional galenic form are distributed between specific biological targets and other anatomical tissues. With the aim to obtain a more rational and a better therapeutic, one of the most promising possibilities by using the concept of vectorization: association of an active principle to an appropriate vector with the object to increase its action efficiency and efficacy. By this means, they do not just increase the affinity of the drug to the target but also active principle gets protected from a potentially hostile environment (hydrolytic enzymes, acid pH, etc.). The success in the extension of the applications of the vectorización depends more and more of an appropriate design, for what the fundamental objective of this revision will be the one of presenting the general characteristics and some of the current applications in these new galenic forms.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: Es Revista: Rev Med Univ Navarra Ano de publicação: 2001 Tipo de documento: Article País de publicação: Espanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: Es Revista: Rev Med Univ Navarra Ano de publicação: 2001 Tipo de documento: Article País de publicação: Espanha