[Controlled liberation of active principles by means of new galenic formulations]. / Liberación controlada de principios activos mediante el empleo de formulaciones galénicas.
Rev Med Univ Navarra
; 45(4): 19-34, 2001.
Article
em Es
| MEDLINE
| ID: mdl-11985214
Drugs inside a conventional galenic form are distributed between specific biological targets and other anatomical tissues. With the aim to obtain a more rational and a better therapeutic, one of the most promising possibilities by using the concept of vectorization: association of an active principle to an appropriate vector with the object to increase its action efficiency and efficacy. By this means, they do not just increase the affinity of the drug to the target but also active principle gets protected from a potentially hostile environment (hydrolytic enzymes, acid pH, etc.). The success in the extension of the applications of the vectorización depends more and more of an appropriate design, for what the fundamental objective of this revision will be the one of presenting the general characteristics and some of the current applications in these new galenic forms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Portadores de Fármacos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Es
Revista:
Rev Med Univ Navarra
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
Espanha