[Congenital long QT syndrome in newborns]. / Syndrome du QT long congénital de révélation néonatale.
Arch Pediatr
; 9(8): 805-9, 2002 Aug.
Article
em Fr
| MEDLINE
| ID: mdl-12205790
ABSTRACT
UNLABELLED The perinatal manifestations of the long QT syndrome are rare, but early diagnosis and therapy are necessary to prevent sudden death. CASE REPORTS A long QT syndrome was diagnosed in two neonates who presented with foetal bradycardia. In one case, a mutation in the gene KCNQ1 was identified, and a long QT syndrome was diagnosed in the mother and two brothers of the neonate. On beta-blocker therapy, one infant became free of long QT syndrome related symptoms, but a sudden death of the second infant occurred. CONCLUSION:
The long QT syndrome should be considered in the differential diagnosis of foetal bradycardia. Early treatment of the neonate and his family may prevent ventricular arrhythmias and sudden death.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bradicardia
/
Síndrome do QT Longo
/
Antagonistas Adrenérgicos beta
/
Canais de Potássio de Abertura Dependente da Tensão da Membrana
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Female
/
Humans
/
Newborn
Idioma:
Fr
Revista:
Arch Pediatr
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
França