Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust.
Am J Respir Crit Care Med
; 166(6): 797-800, 2002 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-12231487
ABSTRACT
We report a sentinel case of acute eosinophilic pneumonia in a firefighter exposed to high concentrations of World Trade Center dust during the rescue effort from September 11 to 24. The firefighter presented with a Pa(O2) of 53 mm Hg and responded to oxygen and corticosteroids. Computed tomography scan showed patchy ground glass density, thickened bronchial walls, and bilateral pleural effusions. Bronchoalveolar lavage recovered 70% eosinophils, with only 1% eosinophils in peripheral blood. Eosinophils were not degranulated and increased levels of interleukin-5 were measured in bronchoalveolar lavage and serum. Mineralogic analysis counted 305 commercial asbestos fibers/10(6) macrophages including those with high aspect ratios, and significant quantities of fly ash and degraded fibrous glass. Acute eosinophilic pneumonia is a rare consequence of acute high dust exposure. World Trade Center dust consists of large particle-size silicates, but fly ash and asbestos fibers may be found in bronchoalveolar lavage cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Eosinofilia Pulmonar
/
Lesão por Inalação de Fumaça
/
Trabalho de Resgate
/
Terrorismo
/
Poeira
/
Incêndios
/
Doenças Profissionais
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Am J Respir Crit Care Med
Assunto da revista:
TERAPIA INTENSIVA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos