Early pregnancy termination with vaginal misoprostol before and after 42 days gestation.
Hum Reprod
; 17(12): 3079-83, 2002 Dec.
Article
em En
| MEDLINE
| ID: mdl-12456606
ABSTRACT
BACKGROUND:
Misoprostol is a prostaglandin E(1) analogue that has been used for medical abortion. We conducted this prospective study to compare the efficacy of vaginal misoprostol for abortion in women at a gestational age of <42 days and in women at a gestational age of 42-56 days.METHODS:
A total of 160 women seeking medical termination of a pregnancy of <56 days were enrolled in the study. Medical termination was performed using 800 micro g of vaginal misoprostol, repeated every 24 h for a maximum of three doses.RESULTS:
The overall complete abortion rate was 91.3%. In group A (gestation <42 days) complete abortion occurred in 96.3% of women, whereas in group B (gestation = 42-56 days) complete abortion occurred in 86.3% of women (P < 0.025). The two groups did not differ significantly with respect to side-effects (incidence of pain, bleeding, nausea, diarrhoea, fever and headache). Women who had aborted successfully were significantly more satisfied with the method compared with women who did not (P < 0.001).CONCLUSIONS:
The vaginal misoprostol-alone regimen is highly effective for women seeking medical abortion of pregnancies of
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Abortivos não Esteroides
/
Idade Gestacional
/
Misoprostol
/
Aborto Induzido
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Hum Reprod
Assunto da revista:
MEDICINA REPRODUTIVA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Grécia