[Cytogenetic aberrations in the cells of liver and spermatogenetic epithelium in senescence accelerated SAMP1 and SAMR1 mice]. / Tsitogeneticheskie aberratsii v kletkakh pecheni i spermatogennogo épiteliia u uskorenno stareiushchikh myshei linii SAMP1 i SAMR1.
Ontogenez
; 33(6): 444-56, 2002.
Article
em Ru
| MEDLINE
| ID: mdl-12500553
ABSTRACT
It was shown that during ontogenesis, the mice prone to (SAMP1) and resistant against accelerates senescence did not differ substantially in the frequency of cytogenetic aberrations in the hepatocytes and spermatogenic cells (spermatozoa and circular spermatids). These data suggest that in the mice of both lines, the processes of appearance, development, and functioning of complex biological systems, such as liver and testis, take place against the background of high genetic instability. The role of genetic instability in senescence is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espermatogônias
/
Aberrações Cromossômicas
/
Fígado
Limite:
Animals
Idioma:
Ru
Revista:
Ontogenez
Ano de publicação:
2002
Tipo de documento:
Article