PCR analysis of Yq microdeletions in infertile males, a study from South India.
Asian J Androl
; 4(4): 265-8, 2002 Dec.
Article
em En
| MEDLINE
| ID: mdl-12508126
ABSTRACT
AIM:
To estimate the frequency of microdeletions in the long arm of Y-chromosome of 20 infertile males from South India.METHODS:
Polymerase chain reaction (PCR) amplification using Y-specific STS of azoospermia factor (AZF) regions i.e., SY 84 for AZFa, SY 127 for AZFb and SY 254 for AZFc.RESULTS:
Of the 20 infertile subjects 3 (15 %), one azoospermic and two oligozoospermic, showed microdeletions in the AZF region of Y-chromosome.CONCLUSION:
The frequency of deletions involving AZF region of the Y-chromosome is 15 % in azoospermic and severely oligozoospermic infertile men. PCR amplification of AZF locus is useful for the diagnosis of microdeletions in the Y-chromosome.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reação em Cadeia da Polimerase
/
Deleção Cromossômica
/
Cromossomos Humanos Y
/
Infertilidade Masculina
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Asian J Androl
Assunto da revista:
MEDICINA REPRODUTIVA
/
UROLOGIA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Índia