Treatment strategies in Landau-Kleffner syndrome and paraictal psychiatric and cognitive disturbances.

ABSTRACT

Psychiatric and cognitive disturbances of the peri-ictal period (i.e., the seizure prodrome and the postictal period) can be considered paraictal disturbances, as they are directly related to the ictal event. There are also certain interictal psychiatric and cognitive disturbances that become apparent concomitantly with the onset of a seizure disorder and remit and/or significantly improve upon its remission. Such disorders also fall under the classification paraictal disorders, and are exemplified by Landau-Kleffner syndrome (LKS), a disorder in which language and psychiatric disturbances begin with the onset of epileptic activity and improve upon its disappearance. In this article, we review the treatment of paraictal cognitive and psychiatric disorders presenting as preictal and postictal psychiatric disturbances and LKS.