Interaction of acidic poly-amino acids with octacalcium phosphate.
J Inorg Biochem
; 95(4): 291-6, 2003 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-12818799
ABSTRACT
Octacalcium phosphate (OCP) hydrolysis into hydroxyapatite (HA) has been investigated in aqueous solutions at different concentrations of poly-L-aspartate (PASP) and poly-L-glutamate (PGLU). In the absence of the polyelectrolytes, the transformation of OCP into HA is complete in 48 h. Both poly-L-aspartate and poly-L-glutamate inhibit OCP hydrolysis. However, PGLU displays a greater inhibiting effect, as a result of the different extent of phase transformation obtained at the same polyelectrolyte concentration. The inhibition takes place through polyelectrolyte adsorption on the (100) face of OCP crystals, which prevents the splitting of OCP crystals along their c-axis and the transformation into the final very long, needle-like, apatitic crystals.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfatos de Cálcio
/
Aminoácidos Acídicos
Idioma:
En
Revista:
J Inorg Biochem
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Itália