Targeting proximal T cell receptor signaling in transplantation.
Transplantation
; 75(12): 1921-7, 2003 Jun 27.
Article
em En
| MEDLINE
| ID: mdl-12829888
ABSTRACT
In the past two decades, an immense amount of information has been generated on the mechanism of T cell receptor (TCR) signaling (also called signal 1). This overview describes the major signalling pathways in the TCR signal transduction cascade and focuses on proximal events in TCR signaling. The review also discusses some of the strategies that target proximal TCR signaling, which are used for preventing graft rejection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imunologia de Transplantes
/
Receptores de Antígenos de Linfócitos T
/
Transdução de Sinais
Limite:
Humans
Idioma:
En
Revista:
Transplantation
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos