Effect of Cuscuta chinensis glycoside on the neuronal differentiation of rat pheochromocytoma PC12 cells.
Int J Dev Neurosci
; 21(5): 277-81, 2003 Aug.
Article
em En
| MEDLINE
| ID: mdl-12850061
Exposure of rat pheochromocytoma PC12 cells to Cuscuta chinensis glycoside induced neuronal differentiation with resulting outgrowth of neurites and increase of acetylcholinesterase activity. A specific inhibitor of mitogen-activated protein kinase (MAPK) kinase, PD98059, prevented this effect of C. chinensis on PC12 cells. These results suggested that C. chinensis glycoside induced neuronal differentiation in PC12 cells linked to the mitogen-activated protein kinase signaling cascade.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetilcolinesterase
/
Medicamentos de Ervas Chinesas
/
Quinases de Proteína Quinase Ativadas por Mitógeno
/
Cuscuta
/
Glicosídeos
/
Neurônios
Limite:
Animals
Idioma:
En
Revista:
Int J Dev Neurosci
Ano de publicação:
2003
Tipo de documento:
Article
País de publicação:
Estados Unidos