Inactivation of ompR promotes precocious swarming and flhDC expression in Xenorhabdus nematophila.
J Bacteriol
; 185(17): 5290-4, 2003 Sep.
Article
em En
| MEDLINE
| ID: mdl-12923104
ABSTRACT
The response regulator OmpR is involved in numerous adaptive responses to environmental challenges. The role that OmpR plays in swarming behavior and swarm-cell differentiation in the symbiotic-pathogenic bacterium Xenorhabdus nematophila was examined in this study. Swarming began 4 h sooner in an ompR mutant strain than in wild-type cells. Precocious swarming was correlated with elevated expression of fliC, early flagellation, and cell elongation. The level of flhDC mRNA was elevated during the early period of swarming in the ompR strain relative to the level in the wild type. These findings show that OmpR is involved in the temporal regulation of flhDC expression and flagellum production and demonstrate that this response regulator plays a role in the swarming behavior of X. nematophila.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regulação Bacteriana da Expressão Gênica
/
Transativadores
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Xenorhabdus
/
Proteínas de Ligação a DNA
/
Mutação
Idioma:
En
Revista:
J Bacteriol
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos