[THe role of portal bacteremia and endotoxinemia in the pathogenesis of multiple organ failure in peritonitis]. / Rol' portal'noi bakteriemii i éndotoksinemii v patogeneze poliorgannoi nedostatochnosti pri peritonite.

ABSTRACT

The indices of portal bacteremia and endotoxinemia, parameters of metabolism, hepatic hemodynamics, the phagocytic function of the liver and leukocyte reaction were studied in 13 patients with diffuse peritonitis of different etiology. Close interconnections of the level of portal toxemia is shown with the degree of activation of the phagocytic function of the liver, changes in hepatic hemodynamics, degree of metabolic disturbances playing an important role in pathogenesis of polyorganic insufficiency as well as the role of leukocytic reaction in microendocrinous regulation of metabolism in peritonitis.