New pyrrolobenzodiazepine antibiotics, RK-1441A and B. II. Isolation and structure.
Agric Biol Chem
; 54(11): 2883-7, 1990 Nov.
Article
em En
| MEDLINE
| ID: mdl-1368648
ABSTRACT
Antibacteriophage antibiotics, RK-1441A and B, related to neothramycin were isolated from the culture broth of Streptomyces sp. and their structures were deduced from spectroscopic analyses. The structure of RK-1441A was 8,11-dihydroxy-3,7-dimethoxy-5-oxo-1H-pyrrolo[2,1-c1,4]benzodiazepine. RK-1441B is a tautomeric mixture at C-3 of the structure, 3,8,11-trihydroxy-7-methoxy-5-oxo-1H-pyrrolo[2,1-c1,4]benzodiazepine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antibacterianos
Idioma:
En
Revista:
Agric Biol Chem
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Japão