Oxidative decarboxylation of naproxen.
J Pharm Sci
; 81(5): 479-82, 1992 May.
Article
em En
| MEDLINE
| ID: mdl-1403685
ABSTRACT
The decarboxylation of naproxen (1H) and its salt (1-) was achieved by means of chemical [Ce(IV) or S2O8(2-)] and electrochemical oxidation. The product patterns were compatible with mechanisms involving single-electron transfer from the pi-system or the carboxylate moiety. The results are discussed in connection with the involvement of electron-transfer processes in the reported phototoxicity of naproxen.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Naproxeno
Idioma:
En
Revista:
J Pharm Sci
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Espanha