[An experimental study of the hepatoprotective properties of phytoecdysteroids and nerobol in carbon tetrachloride-induced liver lesion]. / Eksperimental'noe izuchenie gepatoprotektornykh svoistv fitoékdisteroidov i nerobola pri porazhenii pecheni chetyrekhkhloristym uglerodom.
Eksp Klin Farmakol
; 55(3): 61-5, 1992.
Article
em Ru
| MEDLINE
| ID: mdl-1458171
ABSTRACT
The phytoecdisteroids ecdisterone, turkesterone and cyasterone were administered in a dose of 5 mg/kg per os to rats with hepatitis induced by subcutaneous injections of CCl4. Similarly to the anabolic drug nerobol (10 mg/kg), the above agents not only interfere with the manifestation of the hepatic action of CCl4 (in this case the effect of the phytoecdisteroids is more remarkable) but also favour a more rapid normalization, as compared to the control, of functional and metabolic disorders in the liver. The phytoecdisteroids and nerobol noticeably stimulate the recovery of bile secretion, the synthesis of bilirubin and bile acids, cholesterol excretion.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Intoxicação por Tetracloreto de Carbono
/
Extratos Vegetais
/
Doença Hepática Induzida por Substâncias e Drogas
/
Fígado
/
Metandrostenolona
/
Antídotos
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
Ru
Revista:
Eksp Klin Farmakol
Assunto da revista:
FARMACOLOGIA
Ano de publicação:
1992
Tipo de documento:
Article