The effects of dietary supplementation with n-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: a randomized, double blind trial.
Eur J Clin Invest
; 22(10): 687-91, 1992 Oct.
Article
em En
| MEDLINE
| ID: mdl-1459173
ABSTRACT
STUDY OBJECTIVE:
To determine the effect of dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) on disease variables in patients with rheumatoid arthritis.DESIGN:
Multicenter, randomized, placebo controlled, double blind.SETTING:
Three Danish hospital Departments of Rheumatology. PATIENTS Fifty-one patients with active rheumatoid arthritis. INTERVENTION Random allocation to 12 weeks of treatment with either six n-3 PUFA capsules (3.6 g) or six capsules with fat composition as the average Danish diet. MAINRESULTS:
Significant improvement of morning stiffness and joint tenderness. No significant effect on the four other assessed clinical parameters. No serious side effects.CONCLUSIONS:
Dietary supplementation with n-3 PUFA in patients with rheumatoid arthritis improved two out of six patient reported disease parameters. Further studies are needed to clarify the more precise role of n-3 PUFA in the treatment of rheumatoid arthritis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Ácidos Graxos Ômega-3
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Clin Invest
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Dinamarca