Buckwheat concentrate reduces serum glucose in streptozotocin-diabetic rats.
J Agric Food Chem
; 51(25): 7287-91, 2003 Dec 03.
Article
em En
| MEDLINE
| ID: mdl-14640572
ABSTRACT
The antihyperglycemic effects of chemically synthesized d-chiro-inositol (d-CI), a component of an insulin mediator, have been demonstrated in rats. Buckwheat contains relatively high levels of d-CI thus, it has been proposed as a source of d-CI for reducing serum glucose concentrations in diabetics. The present study evaluates the effects of a buckwheat concentrate, containing d-CI, on hyperglycemia and glucose tolerance in streptozotocin (STZ) rats. In fed STZ rats, both doses of the buckwheat concentrate (containing 10 and 20 mg of d-CI/kg of body weight) were effective for lowering serum glucose concentrations by 12-19% at 90 and 120 min after administration. Findings from this study demonstrate that a buckwheat concentrate is an effective source of d-CI for lowering serum glucose concentrations in rats and therefore may be useful in the treatment of diabetes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sementes
/
Glicemia
/
Extratos Vegetais
/
Fagopyrum
/
Diabetes Mellitus Experimental
/
Hipoglicemiantes
Limite:
Animals
Idioma:
En
Revista:
J Agric Food Chem
Ano de publicação:
2003
Tipo de documento:
Article