Postpartum hemolytic uremic syndrome associated with antiphospholipid antibodies. A case report and review of the literature.
Am J Nephrol
; 12(1-2): 126-33, 1992.
Article
em En
| MEDLINE
| ID: mdl-1492877
ABSTRACT
Postpartum hemolytic uremic syndrome (HUS) is described in a woman with a history of spontaneous abortions and both circulating lupus anticoagulant and anticardiolipin antibody (ACA). After termination of her pregnancy because of severe preeclampsia, ACA blood levels increased simultaneously with the onset of a microangiopathic process associated with severe hypertension and renal failure. Plasma exchange resulted in a rapid decline in ACA levels and immediate improvement in her clinical condition. This case strongly suggests an important causal relationship between ACA and postpartum HUS. The possible mechanisms of ACA-related postpartum HUS and the potential role of plasmapheresis in its treatment are reviewed and discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Puerperais
/
Síndrome Antifosfolipídica
/
Anticorpos Anticardiolipina
/
Síndrome Hemolítico-Urêmica
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Am J Nephrol
Ano de publicação:
1992
Tipo de documento:
Article