Seminal vesicle amyloid: the first example of exocrine cell origin of an amyloid fibril precursor.
J Pathol
; 167(3): 297-303, 1992 Jul.
Article
em En
| MEDLINE
| ID: mdl-1517901
ABSTRACT
Amyloid fibrils have been extracted from seminal vesicles, and a dominant 14 kD amyloid fibril protein has been identified. An antiserum to this protein reacted both with amyloid and with epithelial cells in some normal seminal vesicles. These reactions were blocked with seminal vesicle secretion and seminal vesicle amyloid fibril protein, but not by degraded amyloid fibrils or fibril protein from other types of amyloid. It is concluded that seminal vesicle amyloid is derived from secretory proteins of the seminal vesicles. As such, it is the first amyloid described which appears to be the product of an exocrine secretory cell.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glândulas Seminais
/
Precursor de Proteína beta-Amiloide
/
Glândulas Exócrinas
/
Amiloide
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
J Pathol
Ano de publicação:
1992
Tipo de documento:
Article