Effects of steroid hormones and immunosuppressant drugs on defences against uterine microbial contamination in the rat.
Gynecol Obstet Invest
; 34(1): 31-5, 1992.
Article
em En
| MEDLINE
| ID: mdl-1526529
ABSTRACT
This study used rats as a mammalian model to investigate the effects of steroid hormones and immunosuppressant drugs on uterine microflora. It was shown that prednisolone acetate predisposed to uterine contamination unlike oestradiol, ciclosporin and cyclophosphamide. It therefore appears that the leucocyte component of the immune system does not normally play a role in preventing bacterial colonization of the uterus and that prednisolone is producing its effect via some other mechanism, possibly an effect on cervical mucus.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Útero
/
Hormônios
/
Imunossupressores
Limite:
Animals
Idioma:
En
Revista:
Gynecol Obstet Invest
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Nova Zelândia