Molecular biology of gestational trophoblastic neoplasia: a review.
J Reprod Med
; 49(6): 415-22, 2004 Jun.
Article
em En
| MEDLINE
| ID: mdl-15283047
ABSTRACT
Gestational trophoblastic diseases are interrelated conditions characterized by abnormal growth of chorionic tissues with varying propensitiesfor local invasion and metastases. These diseases are characterized by altered expression of several growth regulatory factors and oncogenes. On the basis of the expression of various oncogenes and growth factors, partial mole appears to be more like normal placenta, while complete mole seems to be more like choriocarcinoma. These results may have both prognostic and therapeutic consequences and provide insight into the relationship between normal placenta and gestational trophoblastic diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Placenta
/
Proto-Oncogenes
/
Regulação Neoplásica da Expressão Gênica
/
Substâncias de Crescimento
/
Doença Trofoblástica Gestacional
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
J Reprod Med
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Estados Unidos