Inherited multicentric osteolysis with carpal-tarsal localisation mimicking juvenile idiopathic arthritis.
Eur J Pediatr
; 163(10): 612-8, 2004 Oct.
Article
em En
| MEDLINE
| ID: mdl-15290262
ABSTRACT
UNLABELLED Five patients with multicentric carpal-tarsal osteolysis are presented a mother and her three children with an autosomal dominant mode of inheritance and one of the children with nephropathy, the fifth a sporadic case also with renal involvement. The main findings common to these five patients are symptoms and signs simulating arthritis of the wrists and/or ankles starting at a young age and mimicking juvenile idiopathic arthritis. Early signs of osteolysis and shortening of the carpus or tarsus are radiological characteristic. The disease may be associated with a peculiar face, but most importantly with nephropathy. The pathogenesis is still unknown. CONCLUSION:
Recognition of this disease and differentiation from juvenile idiopathic arthritis is important to avoid unnecessary investigations and treatment. Follow-up of renal function is indicated.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Juvenil
/
Síndrome de Hajdu-Cheney
Tipo de estudo:
Diagnostic_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Eur J Pediatr
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Holanda