Smooth muscle fraction of the round ligament in women with pelvic organ prolapse: a computer-based morphometric analysis.
Int Urogynecol J Pelvic Floor Dysfunct
; 16(1): 39-43; discussion 43, 2005.
Article
em En
| MEDLINE
| ID: mdl-15365597
Our objective was to compare the collagen and muscle content of the round ligament of uteri in women with pelvic organ prolapse. We evaluated the tissue samples obtained from the round ligaments of 22 patients with uterine prolapse who underwent vaginal hysterectomy (group A, study) and from 26 patients with no pelvic relaxation in whom total abdominal hysterectomy was performed for benign reasons (group B, controls). Morphometric analysis was performed on histologic cross-sections of the round ligament. Sections from each sample were stained with hematoxylin and eosin and Masson's trichrome methods. A computer system was used for morphometric measurements. We used independent samples t-test or Mann-Whitney U test to investigate the difference between the two groups. It was found that the smooth muscle fraction of the round ligament in women with uterine prolapse was significantly decreased compared with that of healthy control subjects and concluded that decreased smooth muscle content may be an important pathogenetic factor in uterine prolapse.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Simulação por Computador
/
Colágeno
/
Ligamento Redondo do Útero
/
Prolapso Uterino
/
Músculo Liso
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Int Urogynecol J Pelvic Floor Dysfunct
Assunto da revista:
GINECOLOGIA
/
UROLOGIA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Turquia
País de publicação:
Reino Unido