The effect of colostrum on pigs pre-natally or post-natally exposed to Schistosoma japonicum.
Parasitology
; 129(Pt 5): 597-604, 2004 Nov.
Article
em En
| MEDLINE
| ID: mdl-15552404
ABSTRACT
Pre-natal infection of Schistosoma japonicum in pigs may prove to be a useful model in shedding light on human pre-natal schistosomiasis. This study describes the effects of immune colostrum on worm burdens, tissue egg counts, liver pathology and crude worm or egg antigen-specific IgG and IgA responses, in groups of pigs pre-natally, pre-natally + post-natally or post-natally exposed to S. japonicum. Results suggest that pre-natal exposure and immune colostrum did not affect the establishment of a post-natal challenge infection. However, immune colostrum seemed to increase the levels of septal fibrosis in pre-natally exposed pigs. These findings indicate that further investigations will prove valuable, elucidating the influence of the parasitological and immunological status of the sow, on pre-natally exposed pigs, and on the ability of these pigs to develop resistance against S. japonicum later in life.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Schistosoma japonicum
/
Doenças dos Suínos
/
Esquistossomose Japônica
/
Complicações Parasitárias na Gravidez
/
Colostro
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Parasitology
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Dinamarca