Virucidal activity presence in Trichilia glabra leaves.
Rev Argent Microbiol
; 36(3): 136-8, 2004.
Article
em En
| MEDLINE
| ID: mdl-15559196
ABSTRACT
Different immunomodulatory activities present in Trichilia glabra (TG) leaf extracts have already been described. Particularly, chloroform-methanol extracts were responsible for an in-vivo anti-inflammatory effect. The effect of such extracts on the infectivity of enveloped and naked viruses were investigated. Methanolic fraction extracts were active against herpes simplex virus type 1 (HSV-1) and vesicular stomatitis virus (VSV), while no activity against poliovirus type 3 was observed. VSV was slightly more affected than HSV-1 2.8 log10 reduction in VSV titer against 2.4 log10 reduction in HSV-1 titer when 0.25 mg/ml F2 fraction was tested and a reduction of 2.7 log10 in VSV virus titer and of 1.5 log10 in HSV-1 virus titer was observed when 0.25 mg/ml F3 fraction was tested. Results obtained in this work suggest a potential pharmaceutical use of TG extract components.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Extratos Vegetais
/
Folhas de Planta
/
Meliaceae
Limite:
Animals
Idioma:
En
Revista:
Rev Argent Microbiol
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Argentina