Your browser doesn't support javascript.
loading
Cognitive and psychiatric evaluation of 40 patients with myotonic dystrophy.
Colombo, G; Perini, G I; Miotti, M V; Armani, M; Angelini, C.
Afiliação
  • Colombo G; Istituto di Clinica Psichiatrica, Università di Padova.
Ital J Neurol Sci ; 13(1): 53-8, 1992 Feb.
Article em En | MEDLINE | ID: mdl-1559784
We evaluated 40 patients suffering from a severe form a myotonic dystrophy (MD) with neuropsychological (WAIS-R, MMSE) and psychiatric tests (SADS, SRT) for the assessment of cognitive and psychiatric symptoms. We tested 20 normal volunteers as control group. Patients with MD scored significantly, lower on WAIS Full Scale (p less than 0.001), Verbal Scale (p less than 0.001), and Performance Scale (p less than 0.001) and on the MMSE (p less than 0.05) than the controls. 35% of patients met the Research Diagnostic Criteria for a psychiatric diagnosis; 17.5% of them had a depressive disorder. The scores on SADS subscales and on the SRT scale of depression were also significantly higher in patients than in controls. Our data confirm that mental impairment and psychiatric disorders are important clinical manifestations of CNS dysfunction in the severe form on MD.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cognição / Distrofia Miotônica Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Ital J Neurol Sci Ano de publicação: 1992 Tipo de documento: Article País de publicação: Itália
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cognição / Distrofia Miotônica Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Ital J Neurol Sci Ano de publicação: 1992 Tipo de documento: Article País de publicação: Itália