[Past, present and future of anti-idiotype vaccination]. / Pasado, presente y futuro de la vacunación anti-idiotipo.
Rev Med Univ Navarra
; 48(3): 14-23, 2004.
Article
em Es
| MEDLINE
| ID: mdl-15622921
ABSTRACT
Cancer vaccines are conceived as therapeutic tools, in contrast to the prophylactic vaccines used to fight against infectious diseases. Among the most potent therapeutic vaccines, anti-idiotype vaccination is directed against the tumor idiotype, the only well-characterized tumor antigen displayed in neoplastic B-cells. Anti-idiotype vaccines have demonstrated clinical benefit against follicular lymphoma and are currently being evaluated in two different phase III clinical trials. Additional emerging strategies, which include the use of dendritic cells and the production of vaccines via molecular means will surely allow us to draw important conclusions concerning the treatment of cancer patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacinas Anticâncer
/
Neoplasias
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Es
Revista:
Rev Med Univ Navarra
Ano de publicação:
2004
Tipo de documento:
Article
País de publicação:
ES
/
ESPANHA
/
ESPAÑA
/
SPAIN