A comparison of propofol, midazolam, and methohexital for sedation during retrobulbar and peribulbar block.
J Clin Anesth
; 4(2): 93-6, 1992.
Article
em En
| MEDLINE
| ID: mdl-1562343
ABSTRACT
STUDY OBJECTIVE:
To compare the efficacy of propofol, methohexital, and midazalom in providing adequate sedation during administration of retrobulbar block and satisfactory postoperative amnesia.DESIGN:
Retrospective chart review over a 4-month period.SETTING:
Ambulatory patients in the main operating room of a university-affiliated hospital. PATIENTS One hundred forty-seven ambulatory patients undergoing ophthalmologic surgery of less than 2 hours' duration under regional anesthesia consisting of retrobulbar or peribulbar block and intravenous (IV) sedation.INTERVENTIONS:
One of three drugs--propofol 0.47 +/- 0.06 mg/kg, midazolam 0.02 +/- 0.005 mg/kg, or methohexital 0.45 +/- 0.16 mg/kg--was administered IV. Patients were observed for a minimum of 60 seconds or until adequate sedation was achieved, after which a retrobulbar or peribulbar block was performed. MEASUREMENTS AND MAINRESULTS:
Blood pressure, electrocardiogram, and oxygen saturation were monitored and recorded. Patients were observed for apnea, hiccups, pain on injection, excitement, tremor, grimacing, or verbal response during the block. The requirement for additional sedation intraoperatively was noted. Patients were questioned postoperatively in the ambulatory recovery room for recall of needle insertion or discomfort during the block, as well as about their satisfaction with the overall experience.CONCLUSIONS:
Grimacing or verbal response during the retrobulbar or peribulbar block did not predict or correlate with patient recall. Propofol was equal to both midazolam and methohexital in providing adequate sedation and postoperative amnesia but possesses the added advantages of reduced postoperative vomiting, lower intraocular pressure, and earlier return-to-home readiness.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Procedimentos Cirúrgicos Oftalmológicos
/
Midazolam
/
Propofol
/
Procedimentos Cirúrgicos Ambulatórios
/
Hipnóticos e Sedativos
/
Metoexital
/
Bloqueio Nervoso
Tipo de estudo:
Health_economic_evaluation
Limite:
Humans
Idioma:
En
Revista:
J Clin Anesth
Assunto da revista:
ANESTESIOLOGIA
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Marrocos