Pattern of pineal melatonin concentrations during prolonged exposure to short photoperiods in photosensitive and photoinsensitive Djungarian hamsters.

ABSTRACT

In the Djungarian hamster (Phodopus sungorus) there is strong evidence that the nightly decompression or lengthening, respectively, of the pineal melatonin pattern is involved in conveying the inhibitory influence of short photoperiods. Some hamsters, however, are insensitive to photoinhibitory influences; other late-responding hamsters show a delayed reaction of several months. The daily pattern of pineal melatonin proves that the mechanisms determining long- or short-day patterns become effective in the morning and evening hours when melatonin concentrations of photoinhibited hamsters are clearly elevated, while those of long-day hamsters are reduced to negligible low values. At two decisive time points in the morning and evening, male and female early-responding photosensitive hamsters were killed after 5, 10, 15, and 20 weeks in short photoperiods, nonresponding hamsters after 10 and 20 weeks, and late-responding after 20 weeks. In all early-responding hamsters changes in gonadal stage, body weight, and pelage color corresponded to the decompression of the nightly melatonin pattern. During prolonged exposure to short photoperiods a decrease of mean melatonin concentrations in the morning and an increase of evening concentrations was observed in both sexes. The lengthening of nightly elevated melatonin concentrations was missing in photoinsensitive hamsters. In late-responding hamsters this decompression seems to be delayed, as melatonin concentrations of female late responders indicate. In conclusion, the lengthening of the melatonin pattern seems to predict a photoperiodic reaction of the effector system. The lengthened pattern of photosensitive hamsters may not be unchangeable, as it may be subjected to modifications during prolonged exposure to short photoperiods.