Vasodilatation of the hindquarters induced by antagonism of GABA(A) receptors in the freely moving rat.
Jpn J Physiol
; 55(1): 75-8, 2005 Feb.
Article
em En
| MEDLINE
| ID: mdl-15796792
ABSTRACT
An intracisternal injection of the GABA(A) receptor antagonist bicuculline into conscious rats increased arterial pressure and decreased hindquarter resistance. Propranolol attenuated only the resistance response, but ganglionic block abolished both responses. These findings suggest that central GABA(A) receptor blockade induces an autonomic pressor action with hindquarter vasodilatation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasodilatação
/
Bicuculina
/
Receptores de GABA-A
/
Antagonistas GABAérgicos
Limite:
Animals
Idioma:
En
Revista:
Jpn J Physiol
Ano de publicação:
2005
Tipo de documento:
Article