Misleading results in the determination of haemolytic disease of the newborn using antibody titration and ADCC in a woman with anti-Lub.
Vox Sang
; 62(1): 49-52, 1992.
Article
em En
| MEDLINE
| ID: mdl-1580067
ABSTRACT
The Lutheran blood group system consists of several genes of which Lua and Lub are the best characterized. Over 98% of the Western population is Lu (b+), and consequently antibody formation against Lub is rare. Cases reported in the literature suggest that the expression of Lutheran antigens on red cells of the newborn is weak, and Lutheran antibodies are not known to have caused severe haemolytic disease of the newborn. We describe a case of anti-Lub immunization during pregnancy. Despite increasing anti-Lub antibody titre and antibody-dependent, cell-mediated cytotoxic activity of the anti-Lub, two parameters associated with haemolytic disease of the newborn, the baby did not suffer from erythroblastosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Eritroblastose Fetal
/
Isoanticorpos
/
Sistema do Grupo Sanguíneo Lutheran
/
Anticorpos
/
Citotoxicidade Celular Dependente de Anticorpos
Limite:
Adult
/
Female
/
Humans
/
Newborn
Idioma:
En
Revista:
Vox Sang
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Holanda