Phytosterols in nonfat and low-fat beverages have no impact on the LDL size phenotype.
Eur J Clin Nutr
; 59(6): 801-4, 2005 Jun.
Article
em En
| MEDLINE
| ID: mdl-15856068
ABSTRACT
OBJECTIVE:
To examine the impact of nonfat and low-fat phytosterol-enriched beverages on low-density lipoprotein (LDL) electrophoretic characteristics.DESIGN:
Double-blind, randomized, crossover, placebo-controlled dietary trial.SETTING:
Diets were prepared and consumed at the Mary Emily Clinical Nutrition Research Unit of McGill University. Analyses were performed at the Institute on Nutraceuticals and Functional Foods of Laval University. SUBJECTS AND INTERVENTION In total, 15 moderately hypercholesterolemic persons consumed each of three experimental diets that each comprised a different beverage nonfat placebo (NF control), nonfat with phytosterols (NFPS) or low-fat with phytosterols (LFPS). Participants consumed three beverages daily at meal time for a total of 1.8 g of phytosterols per day. Nondenaturing 2-16% polyacrylamide gradient gel electrophoreses were used to characterize LDL size characteristics.RESULTS:
The NFPS and LFPS beverage induced no significant changes in several features of the LDL size phenotype compared to the control diet.CONCLUSION:
The consumption of phytosterol-supplemented nonfat and low-fat beverages is not associated with clinically meaningful changes in the LDL particle size phenotype.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fitosteróis
/
Gorduras na Dieta
/
Hipercolesterolemia
/
LDL-Colesterol
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Clin Nutr
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Canadá