Secretion of recombinant pediocin PA-1 by Bifidobacterium longum, using the signal sequence for bifidobacterial alpha-amylase.

Moon, Gi-Seong; Pyun, Yu-Ryang; Park, Myeong Soo; Ji, Geun Eog; Kim, Wang June

Moon, Gi-Seong; Pyun, Yu-Ryang; Park, Myeong Soo; Ji, Geun Eog; Kim, Wang June.

Afiliação

Moon GS; Food Safety Research Division, Korea Food Research Institute, San 46-1, Baekhyun-Dong, Bundang-Gu, Seongnam, Gyeonggi 463-746, Korea.

Appl Environ Microbiol ; 71(9): 5630-2, 2005 Sep.

Article em En | MEDLINE | ID: mdl-16151166

ABSTRACT

ABSTRACT

A recombinant DNA, encoding the chimeric protein of the signal sequence for bifidobacterial alpha-amylase mature pediocin PA-1, was introduced into Bifidobacterium longum MG1. Biologically active pediocin PA-1 was successfully secreted from the strain and showed bactericidal activity against Listeria monocytogenes and the same molecular mass as native pediocin PA-1.

Assuntos

Bacteriocinas/metabolismo; Bifidobacterium/metabolismo; Listeria monocytogenes/efeitos dos fármacos; Sinais Direcionadores de Proteínas; Proteínas Recombinantes/metabolismo; Bacteriocinas/genética; Bacteriocinas/farmacologia; Bifidobacterium/genética; Regulação Bacteriana da Expressão Gênica; Pediocinas; Proteínas Recombinantes/genética; alfa-Amilases/genética; alfa-Amilases/metabolismo

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriocinas / Bifidobacterium / Proteínas Recombinantes / Sinais Direcionadores de Proteínas / Listeria monocytogenes Tipo de estudo: Evaluation_studies Idioma: En Revista: Appl Environ Microbiol Ano de publicação: 2005 Tipo de documento: Article

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google