Plethysmograph and interrupter resistance measurements in prematurely born young children.
Arch Dis Child Fetal Neonatal Ed
; 91(3): F193-6, 2006 May.
Article
em En
| MEDLINE
| ID: mdl-16239293
ABSTRACT
BACKGROUND:
Airways obstruction in premature infants is often assessed by plethysmography, which requires sedation. The interrupter (Rint) technique does not require sedation, but has rarely been examined in children under 2 years of age.OBJECTIVE:
To compare Rint results with plethysmographic measurements of airway resistance (Raw) in prematurely born, young children.DESIGN:
Prospective study.SETTING:
Infant and Paediatric Lung Function Laboratories. PATIENTS Thirty children with a median gestational age of 25-29 weeks and median postnatal age of 13 months. INTERVENTIONS AND MAIN OUTCOMEMEASURES:
The infants were sedated, airway resistance was measured by total body plethysmography (Raw), and Rint measurements were made using a MicroRint device. Further Raw and Rint measurements were made after salbutamol administration if the children remained asleep.RESULTS:
Baseline measurements of Raw and Rint were obtained from 30 and 26 respectively of the children. Mean baseline Rint values were higher than mean baseline Raw results (3.45 v 2.84 kPa/l/s, p = 0.006). Limits of agreement for the mean difference between Rint and Raw were -1.52 to 2.74 kPa/l/s. Ten infants received salbutamol, after which the mean Rint result was 3.6 kPa/l/s and mean Raw was 3.1 kPa/l/s (limits of agreement -0.28 to 1.44 kPa/l/s).CONCLUSION:
The poor agreement between Rint and Raw results suggests that Rint measurements cannot substitute for plethysmographic measurements in sedated prematurely born infants.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pletismografia Total
/
Resistência das Vias Respiratórias
/
Obstrução das Vias Respiratórias
/
Doenças do Prematuro
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Observational_studies
Limite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Arch Dis Child Fetal Neonatal Ed
Assunto da revista:
PEDIATRIA
/
PERINATOLOGIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Reino Unido