Imaging in cell-based therapy for neurodegenerative diseases.
Eur J Nucl Med Mol Imaging
; 32 Suppl 2: S417-34, 2005 Dec.
Article
em En
| MEDLINE
| ID: mdl-16267643
ABSTRACT
Fetal cell transplantation for the treatment of Parkinson's and Huntington's diseases has been developed over the past two decades and is now in early clinical testing phase. Direct assessment of the graft's survival, integration into the host brain and impact on neuronal functions requires advanced in vivo neuroimaging techniques. Owing to its high sensitivity, positron emission tomography is today the most widely used tool to evaluate the viability and function of the transplanted tissue in the brain. Nuclear magnetic resonance techniques are opening new possibilities for imaging neurochemical events in the brain. The ultimate goal will be to use the combination of multiple imaging modalities for complete functional monitoring of the repair processes in the central nervous system.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Diagnóstico por Imagem
/
Doenças Neurodegenerativas
/
Perfilação da Expressão Gênica
/
Transplante de Células-Tronco
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Eur J Nucl Med Mol Imaging
Assunto da revista:
MEDICINA NUCLEAR
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Suécia