[Activated eosinophils: techniques to characterize them]. / Etude de l'activation du polynucléaire éosinophile. Apport des méthodologies classiques et récentes à la caractérisation d'une cellule complexe.
Presse Med
; 35(1 Pt 2): 125-34, 2006 Jan.
Article
em Fr
| MEDLINE
| ID: mdl-16462677
ABSTRACT
The deleterious role thought to be played by eosinophils in many situations is linked to their ability to secrete various inflammatory substances, mainly toxic proteins and lipid mediators, in body tissue. This ability is a particular feature of activated eosinophils, which have undergone numerous metabolic, functional, and phenotypic changes from their resting state. Characterizing the properties of these activated cells is an essential step in improving our understanding of their contributions to local inflammatory response, as both regulatory and effector cells. Improvements in existing methods as well as the development of new technical approaches have facilitated the ex vivo and in vitro study of activated eosinophils and their contribution to various disease states.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Granulares de Eosinófilos
/
Eosinófilos
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Fr
Revista:
Presse Med
Ano de publicação:
2006
Tipo de documento:
Article