The effects of orbital frontal cortex damage on the modulation of defensive responses by rats in playful and nonplayful social contexts.
Behav Neurosci
; 120(1): 72-84, 2006 Feb.
Article
em En
| MEDLINE
| ID: mdl-16492118
ABSTRACT
In a series of 3 experiments on rats, 2 hypotheses were tested (a) that damage to the orbital frontal cortex (OFC) would alter the socially relevant context for executing defensive responses but not their performance and (b) that damage done to the OFC in early infancy would produce more deficits in social behavior than similar damage occurring in adulthood. Bilateral or unilateral OFC damage in adult males did not impair their ability to defend themselves during play fighting and when protecting their food but did impair their ability to modify the pattern of defense in response to different partners. Rats that sustained bilateral damage at 3 days of age not only had deficits in partner-related modulation of defense but also exhibited hyperactivity in their play. The findings thus supported the proposed hypotheses.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Órbita
/
Jogos e Brinquedos
/
Comportamento Social
/
Predomínio Social
/
Comportamento Animal
/
Córtex Pré-Frontal
Aspecto:
Determinantes_sociais_saude
Limite:
Animals
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Canadá