[Influence of selected neonatal diseases on the incidence of gastroesophageal reflux in preterm neonates]. / Wplyw wybranych schorzen okresu noworodkowego na wystepowanie refleksu zoladkowo-przelykowego u noworodków urodzonych przedwczesnie.

ABSTRACT

AIM: To assess the correlation between the incidence of gastroesophageal reflux and chosen neonatal diseases. MATERIAL AND METHODS: Analysis of 106 neonates born before 38 weeks of pregnancy was undertaken. All patients had 24-hour pH-metry and according to the result of this examination we diagnosed or excluded acid gastroesophageal reflux. The correlation between acid gastroesophageal reflux and chosen neonatal diseases, such as congenital infection, intrauterine growth retardation, pneumonia, respiratory distress syndrome, intraventricular hemorrhage, was analyzed. RESULTS: Gastroesophageal reflux was diagnosed in 25 neonates (23.6%). Congenital infection, respiratory distress syndrome, pneumonia and intraventricular hemorrhage showed no influence on the incidence of acid gastroesophageal reflux. Up to 50% of neonates with intrauterine growth retardation had gastroesophageal reflux, whereas in eutrophic neonates it was diagnosed in 16.7% cases. The risk of incidence of gastroesophageal reflux in neonates with intrauterine growth retardation was almost 5 times higher than in eutrophic neonates. CONCLUSIONS: No correlation between gastroesophageal reflux and congenital infection, respiratory distress syndrome, pneumonia, intraventricular hemorrhage has been found. The incidence of gastroesophageal reflux was higher in infants with intrauterine growth retardation.