Cellular contributions to glomerular size-selectivity.
Kidney Int
; 69(8): 1295-7, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16612411
ABSTRACT
The glomerular capillary wall permits free passage of low-molecular-weight solutes, while severely restricting large proteins. Although both cell layers (endothelium and epithelium) almost certainly contribute to this size-selectivity, their relative importance has been difficult to assess. The finding by Rippe et al. of an inverse relationship between the sieving coefficient of Ficoll and glomerular filtration rate sheds light on this.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Endotélio
/
Epitélio
/
Ficoll
/
Glomérulos Renais
Limite:
Animals
Idioma:
En
Revista:
Kidney Int
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos