[Cervico-vaginal infection by HPV: cyto-histological morphology in the different viral strains]. / Infezione cervicovaginale da HPV: morfologia citoistologica nei differenti tipi virali.
Ann Ostet Ginecol Med Perinat
; 112(3): 135-45, 1991.
Article
em It
| MEDLINE
| ID: mdl-1667459
ABSTRACT
One-hundred ten cervical or vaginal bioptic samples have been submitted to in-situ HPV typing with biotinylated probes. All samples had been taken from women with colposcopic findings suggesting HPV infection, and at histopathology showed koilocytosis sometimes associated with CIN or VAIN. Sixty-four samples were positive (16 for HPV 6/11 - 37 for HPV 16/18, 11 for HPV 31/35/51). Histopathological and cytological specimens were reviewed to detect the possible existence of morphological patterns typical of the various viral types. Papillomatosis, slightly increased nuclear size with finely granular chromatin, low number of mitoses, and scarce cyto-polymorphism, were associated with HPV 6/11, as well as the absence of intraepithelial neoplasia. A higher number of mitoses (and/or atypical ones), cyto-polymorphism, association with intraepithelial neoplasia, nuclear vacuolization, nuclei of increased size, with irregular borders, hyperchromic, with dark and lumpy chromatin were indicative of high or medium risk HPV (16/18 or 31/35/51). In cytological smears also the finding of dyskeratocytes was associated with these viral types, while multiple nuclei were present in the case of HPV 31/35/51 detection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Infecções Tumorais por Vírus
/
Vaginite
/
Cervicite Uterina
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
It
Revista:
Ann Ostet Ginecol Med Perinat
Ano de publicação:
1991
Tipo de documento:
Article
País de publicação:
IT
/
ITALIA
/
ITALY
/
ITÁLIA