Shift in the epidemiology of pertussis infection: an indication for pertussis vaccine boosters for adults?
Drugs
; 66(6): 731-41, 2006.
Article
em En
| MEDLINE
| ID: mdl-16706548
ABSTRACT
Pertussis vaccination of young children has been effective in reducing the overall disease burden due to Bordetella pertussis in many countries. However, the disease has not been eliminated, although humans are the only known host of this pathogen. In fact, in some countries, the number of reported cases has increased dramatically from their nadir and epidemics routinely occur. In areas where >80% of children <2 years of age have been vaccinated, the burden of disease has shifted from elementary school-aged children (who are presumably protected by vaccination) to young infants (<6 months of age) and individuals >11 years of age. With the recent availability of acellular pertussis vaccines for older children to adults, consideration of a change in current vaccination policy is necessary in order to provide better disease control.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bordetella pertussis
/
Vacina contra Coqueluche
/
Coqueluche
/
Imunização Secundária
Tipo de estudo:
Screening_studies
/
Sysrev_observational_studies
Aspecto:
Implementation_research
Limite:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Middle aged
País/Região como assunto:
America do norte
/
Europa
/
Oceania
Idioma:
En
Revista:
Drugs
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos