Reduction in antimicrobial substantivity of MTAD after initial sodium hypochlorite irrigation.
J Endod
; 32(10): 970-5, 2006 Oct.
Article
em En
| MEDLINE
| ID: mdl-16982276
ABSTRACT
Potential intrinsic tetracycline staining of intraradicular dentin has been observed when BioPure MTAD was employed as the final irrigant after initial rinsing with NaOCl. This study examined the effect of NaOCl-MTAD interaction on the antimicrobial substantivity of MTAD in dentin. Dentin cores previously irrigated with either MTAD, or in conjunction with 1.3% NaOCl as an initial irrigant were placed on blood agar plates inoculated with Escherichia faecalis at 10(5) cfu/ml. Dentin cores irrigated with 1.3% NaOCl only, and autoclaved dentin disks were used as the respective positive and negative controls. After anaerobic incubation, the mean diameter of bacterial inhibition zones formed around the MTAD group was significantly larger than the NaOCl/MTAD group, which, in turn, was not significantly different from the NaOCl positive control. Oxidation of MTAD by NaOCl resulted in the partial loss of antimicrobial substantivity in a manner similar to the peroxidation of tetracycline by reactive oxygen species.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polissorbatos
/
Irrigantes do Canal Radicular
/
Hipoclorito de Sódio
/
Doxiciclina
/
Ácido Cítrico
/
Antibacterianos
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
J Endod
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos