Detecting fetomaternal hemorrhage by flow cytometry.
Curr Opin Hematol
; 13(6): 490-5, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17053464
ABSTRACT
PURPOSE OF REVIEW The aim of this review is to summarize the most recent developments in the area of detection of fetomaternal hemorrhage by flow cytometry. RECENT FINDINGS:
Maternal red blood cell chimerism is readily detectable by flow cytometry. Fetal and maternal red blood cells differ in their content of fetal hemoglobin (alpha2gamma2). Fetal red blood cells contain fetal hemoglobin, and normal maternal red blood cells contain some percentage of fetal hemoglobin in a background of normal adult hemoglobin. All blood group systems with allelic differences between mother and fetus are readily applicable for detection of fetomaternal hemorrhage by fetal hemoglobin.SUMMARY:
Fetal hemoglobin for detection of fetomaternal hemorrhage is an accurate clinical diagnostic procedure for investigation of anemia in fetus and newborn.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemoglobina Fetal
/
Transfusão Feto-Materna
/
Citometria de Fluxo
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Curr Opin Hematol
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Dinamarca