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Axillary regional recurrence after sentinel lymph node biopsy for breast cancer.
Rosing, David K; Dauphine, Christine E; Vargas, M Perla; Gonzalez, Katherine; Burla, Melissa; Kaufmann, Paul; Vargas, Hernan I.
Afiliação
  • Rosing DK; Department of Surgery, Harbor-UCLA Medical Center, Torrance, California, USA.
Am Surg ; 72(10): 939-42, 2006 Oct.
Article em En | MEDLINE | ID: mdl-17058740
The accuracy of sentinel lymph node biopsy (SLNB) staging in breast cancer has been demonstrated in studies comparing it with axillary dissection. There is a 5 per cent false-negative rate, but this does not always correlate with axillary recurrence. Our purpose was to determine the rate of axillary lymphatic recurrence in breast cancer patients who had a negative SLNB. We conducted a cohort study of breast cancer patients who underwent SLNB between 2001 and 2005. Only patients who had a negative SLNB were included. Patient demographics and tumor factors were reviewed. Outcomes measured were axillary and systemic recurrence and survival. Eighty-nine patients with a mean age of 54.4 +/- 9.9 years were included. Eighty-nine per cent of cases had infiltrating ductal carcinoma histology. Mean tumor size was 19 +/- 14 mm. Breast conservation surgery was done in 65 cases and mastectomy in 24. A mean of 2.3 +/- 2.4 SLN were found. After a median follow-up of 2.15 years, 1 (1%) patient developed a lymphatic recurrence in the axilla. SLNB provides accurate staging of breast cancer. Patients with negative SLNB do not require axillary dissection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biópsia de Linfonodo Sentinela / Linfonodos / Recidiva Local de Neoplasia Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Am Surg Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biópsia de Linfonodo Sentinela / Linfonodos / Recidiva Local de Neoplasia Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Am Surg Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos