Recombinant activated factor seven in acute life-threatening bleeding in neonates: report on three cases and review of literature.
J Perinatol
; 26(11): 706-13, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17066067
ABSTRACT
INTRODUCTION:
Acute bleeding of different genesis can be a severe, life-threatening problem in neonatology. Recombinant factor seven (rFVIIa) is known to have unique hemostatic properties in adults and older children. CASE PRESENTATION Three cases of acute life-threatening peri- and postnatal hemorrhage were successfully controlled after the application of fFVIIa. All infants were first treated with vitamin K, fresh-frozen plasma and platelet transfusion.CONCLUSION:
The cases substantiate other reports that rFVIIa is an effective treatment for acute, refractory and life-threatening bleeding in neonates and premature infants.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Recombinantes
/
Fator VII
/
Hemorragia
/
Doenças do Prematuro
Limite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
J Perinatol
Assunto da revista:
PERINATOLOGIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Alemanha