Collecting duct carcinoma of the kidney: a case report with variable immunohistochemistry.

ABSTRACT

BACKGROUND: Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course. AIMS: We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management. RESULTS: Our patient died shortly after commencing systemic chemotherapy. CONCLUSION: Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.