Cannabinoids and PPARalpha signalling.
Biochem Soc Trans
; 34(Pt 6): 1095-7, 2006 Dec.
Article
em En
| MEDLINE
| ID: mdl-17073758
ABSTRACT
Cannabinoids have been shown to possess anti-inflammatory and neuroprotective properties, which were proposed to occur mainly via activation of the G-protein-coupled receptor CB(1) (cannabinoid receptor 1). Recently, certain cannabinoids have been reported to be ligands for members of the nuclear receptor transcription factor superfamily known as PPARs (peroxisome-proliferator-activated receptors). This review summarizes the evidence for cannabinoid activation of PPARs and identifies a new intracellular target for cannabinoids as therapeutic agents for neuroprotective treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Canabinoides
/
Transdução de Sinais
/
PPAR alfa
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Biochem Soc Trans
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Reino Unido